Improving heart imaging for children with cardiomyopathy
Official title: Non-contrast 3D T1p Mapping for Myocardial Fibrosis Quantification of Pediatric Cardiomyopathy Patients
Funded at Cedars-Sinai Medical Center · NIH-11223580 · Data updated 2026-11-12
This study is testing a new way to take heart pictures without using any dyes, making it safer for kids with heart problems, so doctors can better see and understand their heart health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | December 9, 2024 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $248,970 |
| NIH project number | 4R00HL161469-03 |
| Project ID | NIH-11223580 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pediatric patients diagnosed with cardiomyopathy or related heart conditions.
✕Less likely to help
Patients with heart conditions that do not involve myocardial fibrosis may not benefit from this research.
What this research studies
This research focuses on developing a new imaging technique called non-contrast 3D T1p mapping to better detect myocardial fibrosis in pediatric patients with cardiomyopathy. Current imaging methods require contrast agents that can pose risks, especially for children, and often necessitate sedation due to breath-holding requirements. The new approach aims to provide clearer images without the need for contrast, making it safer and more effective for young patients. By using advanced imaging technology, the study seeks to enhance the understanding and management of heart conditions in children.
Why it matters
Potential benefit: If successful, this research could lead to safer and more accurate heart imaging for children, improving diagnosis and treatment of cardiomyopathy.
How similar studies have gone: While traditional imaging techniques have been widely used, this novel approach of non-contrast 3D T1p mapping has not been extensively tested in pediatric populations, making it a potentially groundbreaking advancement.
Where this research is happening
-
Cedars-Sinai Medical Center
Los Angeles, United States Active
Researchers
- Principal investigator: Gunasekaran, Suvai — Cedars-Sinai Medical Center
- Study coordinator: Gunasekaran, Suvai
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.