Improving heart imaging for children with cardiomyopathy

Non-contrast 3D T1p Mapping for Myocardial Fibrosis Quantification of Pediatric Cardiomyopathy Patients

['FUNDING_OTHER'] · CEDARS-SINAI MEDICAL CENTER · NIH-11223580

This study is testing a new way to take heart pictures without using any dyes, making it safer for kids with heart problems, so doctors can better see and understand their heart health.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorCEDARS-SINAI MEDICAL CENTER (nih funded)
Locations1 site (LOS ANGELES, UNITED STATES)
Trial IDNIH-11223580 on ClinicalTrials.gov

What this research studies

This research focuses on developing a new imaging technique called non-contrast 3D T1p mapping to better detect myocardial fibrosis in pediatric patients with cardiomyopathy. Current imaging methods require contrast agents that can pose risks, especially for children, and often necessitate sedation due to breath-holding requirements. The new approach aims to provide clearer images without the need for contrast, making it safer and more effective for young patients. By using advanced imaging technology, the study seeks to enhance the understanding and management of heart conditions in children.

Who could benefit from this research

Good fit: Ideal candidates for this research are pediatric patients diagnosed with cardiomyopathy or related heart conditions.

Not a fit: Patients with heart conditions that do not involve myocardial fibrosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more accurate heart imaging for children, improving diagnosis and treatment of cardiomyopathy.

How similar studies have performed: While traditional imaging techniques have been widely used, this novel approach of non-contrast 3D T1p mapping has not been extensively tested in pediatric populations, making it a potentially groundbreaking advancement.

Where this research is happening

LOS ANGELES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.