Improving heart health for mothers and children in Nigeria during pregnancy and early childhood

ENhancing Intergenerational HeAlth in Nigeria: Peripartum as Critical Life StagE for CardioVascular Health (ENHANCE-CVH)

NIH-funded research Washington University · NIH-11171758

This project will try a home-based healthy eating and activity program for pregnant women with obesity in Nigeria to help mothers and their children have healthier hearts.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11171758 on NIH RePORTER

What this research studies

You could join if you are a pregnant woman with obesity in Nigeria and want support for healthier eating and activity during pregnancy and after birth. The team will adapt a HOME-delivered HEALTH program to teach practical diet and physical activity changes and link families with local health services. About 1,000 pregnant women and their babies will be followed to track weight, blood pressure, and other heart-health measures over time. The researchers will compare families who get the program with those who receive usual care and work with Nigerian health policies to make the program practical to use more widely.

Who could benefit from this research

Good fit: Pregnant women with obesity living in the Nigerian study areas (and their infants) are the intended participants.

Not a fit: People who are not pregnant, do not have obesity, or live outside the study locations in Nigeria are unlikely to be eligible or to benefit directly from this project.

Why it matters

Potential benefit: If successful, the program could help mothers with obesity have healthier pregnancies and lower future heart disease risk for both mothers and their children.

How similar studies have performed: Home-based diet and activity programs have improved weight and lifestyle in other settings, but they are less tested for pregnant women with obesity in Nigeria, so this approach is partly novel for this population.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseases
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.