Improving heart health for mothers and children in Nigeria.
Official title: ENhancing Intergenerational HeAlth in Nigeria: Peripartum as Critical Life StagE for CardioVascular Health (ENHANCE-CVH)
Funded at Washington University · NIH-10920428 · Data updated 2026-11-12
This study is all about helping moms and their kids in Nigeria live healthier lives by encouraging better eating and more physical activity during pregnancy and early childhood, and it’s looking for 1,000 pregnant women with obesity to join in on a program called HEALTH that aims to make a positive difference for their families.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 5, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $562,259 |
| NIH project number | 5R01HL168771-02 |
| Project ID | NIH-10920428 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are pregnant women in Nigeria who are experiencing obesity.
✕Less likely to help
Patients who are not pregnant or do not have obesity may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing cardiovascular health among mothers and their children in Nigeria, particularly during critical life stages such as pregnancy and early childhood. It aims to implement a tailored intervention called HEALTH (Healthy Eating Active Living Taught at Home) to promote better dietary habits and physical activity among pregnant women with obesity. By recruiting 1,000 participants, the study will assess the effectiveness of this intervention in improving maternal health behaviors and reducing the risk of noncommunicable diseases in families. The approach includes leveraging national health policies to support sustainable health improvements.
Why it matters
Potential benefit: If successful, this research could lead to significant improvements in cardiovascular health for mothers and their children, potentially reducing maternal and child mortality rates.
How similar studies have gone: Other research has shown success in implementing health interventions targeting maternal and child health, indicating potential for positive outcomes in this study.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Huffman, Mark D — Washington University
- Study coordinator: Huffman, Mark D
Related research
Other NIH-funded projects on the same topics.
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Enhancing Intergenerational Heart Health in Nigeria during Pregnancy and Early Life
A research project will test a healthy eating and active living program for pregnant women with obesity in Nigeria to help improve heart health for the mother and her children.
-
COVID-19 healthcare disruptions and heart health inequities in NYC adults with multiple conditions
This project looks at how COVID-19-related gaps in care affected heart health in adults with several chronic conditions in New York City.
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ENRICH: A Center to Support Healthy Hearts for Moms and Kids
A nationwide effort at Johns Hopkins to test a consistent, family-focused program that helps mothers and their children develop healthier heart habits using home visiting, technology, and coordinated care.
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Early life air pollution and kids’ heart health: how metals in the air affect children from birth to age 12
This grant studies how pollution from cooking fires and wood smoke in early life may shape a child’s heart health through age 12.
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Enhancing cardiovascular health for moms and kids at home
A multi-center program tests whether enhanced home visiting can improve heart health and growth in families from economically challenged communities by collecting more accurate pediatric height/weight data.
-
GLP-1 receptor drugs and heart-brain health in diabetes and Alzheimer’s risk
A Duke-led study will explore how GLP-1 receptor medicines and exercise affect brain and heart health in models prone to diabetes and Alzheimer’s risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.