Improving heart health by treating sleep problems
Strengthening Hearts by Addressing DisruptEd Sleep (SHADES) Mechanistic Trial
This study is looking at how trouble sleeping might affect heart health, and it’s for adults with insomnia who will try a special therapy to see if it helps them sleep better and lowers their risk of heart problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-11160058 on NIH RePORTER |
What this research studies
This research investigates the link between insomnia and cardiovascular disease (CVD), aiming to identify how sleep issues can contribute to heart problems. It focuses on understanding the biological mechanisms behind this relationship, such as inflammation and metabolic changes. The study will involve adults with insomnia, who will receive cognitive-behavioral therapy for insomnia (CBT-I) to see if it reduces their risk of developing CVD. By addressing sleep disorders, the research seeks to improve overall heart health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who experience insomnia and are at risk for cardiovascular disease.
Not a fit: Patients who do not have insomnia or existing cardiovascular issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing cardiovascular disease by effectively treating insomnia.
How similar studies have performed: Previous research has shown promising results in using cognitive-behavioral therapy for insomnia to reduce inflammation markers associated with cardiovascular disease.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Stewart, Jesse C — Indiana University Indianapolis
- Study coordinator: Stewart, Jesse C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.