Improving heart failure treatment by analyzing heart electrical and mechanical function

Integrative analysis of electrical and mechanical dyssynchrony to improve cardiac resynchronization therapy

NIH-funded research Michigan Technological University · NIH-10875847

This study is looking to improve heart failure treatment by using new technology to better understand how the heart beats and to help doctors choose the best patients for a special therapy that can help their hearts work more effectively.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionMichigan Technological University NIH-funded
Lab location1 site (Houghton, United States)
Project IDNIH-10875847 on NIH RePORTER

What this research studies

This research aims to enhance cardiac resynchronization therapy (CRT) for heart failure patients by analyzing both electrical and mechanical dyssynchrony of the heart. The study will utilize advanced imaging techniques and machine learning algorithms to better select patients who are likely to benefit from CRT and optimize the placement of the therapy device. By integrating data from electrocardiograms and myocardial perfusion imaging, the research seeks to improve clinical decision-making and patient outcomes. This approach addresses the limitations of current methods that often fail to identify the right candidates for CRT.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with heart failure who are being considered for cardiac resynchronization therapy.

Not a fit: Patients who do not have heart failure or those who are not candidates for cardiac resynchronization therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the effectiveness of cardiac resynchronization therapy for heart failure patients, leading to better clinical outcomes.

How similar studies have performed: Previous research has shown promise in using machine learning and imaging techniques to improve patient selection for cardiac therapies, indicating that this approach could yield significant advancements.

Where this research is happening

Houghton, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.