NIH-funded research R01 grant

Improving heart disease risk assessment for dialysis patients

Official title: Redefining cardiovascular risk assessment in dialysis patients (ROCK-D) study

Funded at Indiana University Indianapolis · NIH-11088248 · Data updated 2026-11-12

This study is looking for better ways to predict heart disease risk in people with Chronic Kidney Disease who are on dialysis, so they can get the right care and improve their health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis
NIH-funded
Lab location1 site (Indianapolis, United States)
Project startApril 1, 2023
Project endMarch 31, 2028
Funding year2025
Award (this year)$682,134
NIH project number5R01HL166747-03
Project IDNIH-11088248 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients with Chronic Kidney Disease, particularly those undergoing dialysis.

Less likely to help

Patients without Chronic Kidney Disease or those not on dialysis may not benefit from this research.

What this research studies

This research aims to develop better tools for predicting cardiovascular risk in patients with Chronic Kidney Disease (CKD), particularly those on dialysis. Current methods often underestimate the risk of heart disease in these patients, leading to inadequate care. The study will explore new approaches, including assessing coronary artery calcification and myocardial fibrosis, as well as evaluating cardiovascular function through exercise testing. By identifying more accurate risk factors, the research seeks to enhance patient outcomes and inform clinical practices.

Why it matters

Potential benefit: If successful, this research could lead to more accurate cardiovascular risk assessments, ultimately improving treatment and outcomes for dialysis patients.

How similar studies have gone: While traditional methods have shown limitations, this research explores novel approaches that have not been extensively tested in CKD populations.

Where this research is happening

  • Indiana University Indianapolis
    Indianapolis, United States
    Active

Researchers

  • Principal investigator: Lim, Kenneth — Indiana University Indianapolis
  • Study coordinator: Lim, Kenneth

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.