Improving heart disease prevention for children in Uganda
Accelerating Delivery of rheumatic heart disease preventive iNterventions in Uganda (ADUNU)
This study is working to help kids and young adults in Uganda who might have rheumatic heart disease by using a community program that includes easy heart checks and regular antibiotic treatments right in their neighborhoods.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-10914151 on NIH RePORTER |
What this research studies
This research aims to enhance the prevention of rheumatic heart disease (RHD) among children and young adults in Uganda by implementing a community-based program. The program will utilize handheld echocardiography for RHD testing and a nurse-led approach to deliver monthly antibiotic prophylaxis to those diagnosed. By partnering with the Ugandan government, the project seeks to identify undiagnosed cases of RHD and provide necessary treatment close to patients' homes. The initiative will be tested in two districts to establish a model that can be expanded nationally.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and young adults under 15 years old living in Uganda who are at risk for or have been diagnosed with rheumatic heart disease.
Not a fit: Patients outside of Uganda or those over 15 years old may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of rheumatic heart disease in Uganda, improving health outcomes for affected children and young adults.
How similar studies have performed: Similar community-based approaches have shown success in other regions, indicating potential for effective implementation in Uganda.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Beaton, Andrea Zawacki — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Beaton, Andrea Zawacki
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.