Improving health outcomes for patients with Multiple Myeloma
Official title: Moving Forward with Multiple Myeloma
Funded at Medical College of Wisconsin · NIH-11106702 · Data updated 2026-11-12
This study is looking at how lifestyle changes can help older adults and African Americans with Multiple Myeloma feel better and live healthier by tackling problems like muscle loss and obesity, so they can have more energy and move around easier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | March 10, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $657,844 |
| NIH project number | 1R01CA300310-01 |
| Project ID | NIH-11106702 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults diagnosed with Multiple Myeloma, especially those who are African American and may be experiencing issues related to muscle mass and obesity.
✕Less likely to help
Patients who are not diagnosed with Multiple Myeloma or who do not have significant issues related to physical functioning may not benefit from this research.
What this research studies
This research focuses on enhancing the health and quality of life for patients diagnosed with Multiple Myeloma, particularly among older adults and African Americans. It investigates the impact of lifestyle interventions aimed at improving physical functioning, addressing issues like muscle loss and obesity that are common in these patients. By examining the effects of these interventions on fatigue, mobility, and overall health, the research aims to provide valuable insights into improving patient care and outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved physical health and quality of life for patients with Multiple Myeloma.
How similar studies have gone: Previous research has shown that lifestyle interventions can significantly improve health outcomes in cancer patients, suggesting a promising avenue for this study.
Where this research is happening
-
Medical College of Wisconsin
Milwaukee, United States Active
Researchers
- Principal investigator: Stolley, Melinda R — Medical College of Wisconsin
- Study coordinator: Stolley, Melinda R
Related research
Other NIH-funded projects on the same topics.
-
Integrative study of multiple myeloma genetics and disease biology
A team at Dana-Farber and partners is pursuing a long-term project to understand the genetic and molecular drivers of multiple myeloma and how treatments interact with disease biology.
-
Comparative Modeling to Prevent, Detect Early, and Treat Multiple Myeloma
A research team will build and compare computer models to understand how multiple myeloma develops, can be detected earlier, and treated more effectively.
-
How LDL Affects Multiple Myeloma: New Pathways to Keep Remission
A new grant is studying how cholesterol from LDL particles fuels multiple myeloma and how this interaction influences the tumor environment and immune response, with goals to help patients stay in remission.
-
Therapy-induced senescence and immune activation in multiple myeloma
A study in people with multiple myeloma will explore how treatment-related senescence in cancer cells may stimulate the immune system and affect cancer return after standard frontline therapy.
-
BCMA CAR-T enteritis: understanding immune toxicities in multiple myeloma
A broad study to uncover why some CAR-T cell treatments targeting BCMA cause severe intestinal inflammation in people with multiple myeloma.
-
Understanding Drug-Resistant Multiple Myeloma to Stop Relapse
Researchers are studying why some myeloma cells resist treatment and how to create new therapies to prevent relapse.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.