Improving health outcomes for patients with inflammatory bowel disease.
Official title: RFA-DP-23-002, Improving Outcomes and Reducing Disparities for Patients with Inflammatory Bowel Disease through Epidemiology, Enhanced Disease Management, Dissemination, and Education
Funded at Univ of North Carolina Chapel Hill · NIH-10895259 · Data updated 2026-11-12
This study is looking at how things like your social life and support can impact the health of people with inflammatory bowel disease (IBD), like Crohn's disease and ulcerative colitis, and it will involve 1,200 participants trying out new ways to improve care while also creating helpful resources for patients and doctors.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 30, 2023 |
| Project end | September 29, 2028 |
| Funding year | 2024 |
| Award (this year) | $774,997 |
| NIH project number | 5U01DP006745-02 |
| Project ID | NIH-10895259 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include children aged 13-17 and adults over 17 who are diagnosed with inflammatory bowel disease.
✕Less likely to help
Patients with inflammatory bowel disease who are not willing or able to participate in a clinical trial may not benefit from this research.
What this research studies
This research focuses on understanding how social factors affect the health of individuals with inflammatory bowel disease (IBD), which includes conditions like Crohn's disease and ulcerative colitis. It aims to improve patient care through a multi-center clinical trial involving 1,200 participants, where innovative management strategies will be tested alongside a study of social determinants impacting disease outcomes. The project will also develop educational programs for both patients and healthcare providers to enhance awareness and treatment effectiveness.
Why it matters
Potential benefit: If successful, this research could lead to improved quality of life and reduced health disparities for patients with inflammatory bowel disease.
How similar studies have gone: Previous research has shown that addressing social determinants of health can significantly improve outcomes in chronic disease management, suggesting a promising approach in this area.
Where this research is happening
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Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Kappelman, Michael D — Univ of North Carolina Chapel Hill
- Study coordinator: Kappelman, Michael D
Related research
Other NIH-funded projects on the same topics.
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Mitochondrial Talks: How Energy Networks Shape Inflammatory Bowel Disease
Aimed at people with inflammatory bowel disease (IBD), this project explores how tiny cell powerhouses in the gut may go out of balance and contribute to IBD, with the goal of restoring energy and reducing disease symptoms.
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Mn in inflammatory bowel disease: how manganese and genes may shape gut inflammation
This grant studies how the mineral manganese and a specific gene variant may influence inflammatory bowel disease in people of different ages.
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AI-Enhanced Virtual Reality CBT to Reduce Anxiety for IBD Patients
A home-based VR and AI-powered cognitive behavioral therapy program is being tested to help people with inflammatory bowel disease feel less anxious and improve their quality of life.
-
Gasdermin-based epithelial function in inflammatory bowel disease
A funding opportunity that explores how gasdermin proteins affect the lining of the gut and may influence inflammatory bowel disease.
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Intestinal chondroitin sulfate glycosaminoglycans and their role in inflammatory bowel disease
A clinician-scientist mentoring program aims to advance understanding of how intestinal sugar molecules called chondroitin sulfate glycosaminoglycans influence inflammatory bowel disease and patient care.
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Improving IBD outcomes through community awareness, referrals, and education
A U01 grant will support programs to raise awareness, improve referrals, and educate patients and clinicians about inflammatory bowel disease to improve diagnosis and care.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.