Improving health and well-being for individuals with Down syndrome

Down Syndrome Clinical Cohort Coordinating Center (DS-4C) for the INCLUDE Project

['FUNDING_OTHER'] · RESEARCH TRIANGLE INSTITUTE · NIH-11015426

This study is working to improve the health and well-being of people with Down syndrome by collecting important health information and samples from a diverse group of participants, making sure their voices are heard in the research process.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorRESEARCH TRIANGLE INSTITUTE (nih funded)
Locations1 site (RESEARCH TRIANGLE PARK, UNITED STATES)
Trial IDNIH-11015426 on ClinicalTrials.gov

What this research studies

This research aims to enhance the health and quality of life for individuals with Down syndrome by coordinating a comprehensive data collection program. The INCLUDE Clinical Cohort Coordinating Center (DS-4C) will oversee the development of a unified protocol for data collection across various research sites, ensuring that information is harmonized and accessible. By gathering detailed phenotyping data and biospecimens from a diverse group of participants, the project seeks to support future research focused on Down syndrome-related health issues. Patients will be engaged in outreach efforts to ensure their voices are included in the research process.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals of all ages with Down syndrome who are willing to participate in data collection and provide biospecimens.

Not a fit: Patients without Down syndrome or those who are unable to participate in data collection may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments and interventions for individuals with Down syndrome, addressing co-morbidities and enhancing overall health outcomes.

How similar studies have performed: Previous research initiatives focusing on coordinated data collection in genetic conditions have shown promise, indicating that this approach could yield valuable insights.

Where this research is happening

RESEARCH TRIANGLE PARK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.