Improving health and well-being for individuals with Down syndrome

Down Syndrome Clinical Cohort Coordinating Center (DS-4C) for the INCLUDE Project

['FUNDING_OTHER'] · RESEARCH TRIANGLE INSTITUTE · NIH-11015425

This study is working to improve the health and well-being of people with Down syndrome by gathering important information and samples from a large group of participants, which will help researchers better understand and address related health issues.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorRESEARCH TRIANGLE INSTITUTE (nih funded)
Locations1 site (RESEARCH TRIANGLE PARK, UNITED STATES)
Trial IDNIH-11015425 on ClinicalTrials.gov

What this research studies

This research aims to enhance the health and quality of life for individuals with Down syndrome by coordinating a comprehensive data collection and research program. The INCLUDE Clinical Cohort Coordinating Center (DS-4C) will oversee the development of a unified protocol for data collection across various research sites, ensuring that data is harmonized and accessible for future studies. By creating a large, diverse cohort and collecting detailed phenotyping data and biospecimens, the project seeks to address co-morbidities associated with Down syndrome and support ongoing research efforts.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals of all ages with Down syndrome who are willing to contribute to research efforts.

Not a fit: Patients without Down syndrome or those who are unable to participate in data collection efforts may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and targeted interventions for individuals with Down syndrome.

How similar studies have performed: Previous research initiatives focusing on coordinated data collection in similar populations have shown promise in improving health outcomes and advancing understanding of genetic conditions.

Where this research is happening

RESEARCH TRIANGLE PARK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.