Improving healing of tendon-to-bone connections after rotator cuff surgery
Biomimetic approaches for enthesis tissue engineering
This study is looking at new ways to help your shoulder heal better after rotator cuff surgery by creating special materials that act like healthy tendons, which could lead to a smoother recovery and better shoulder function.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10994155 on NIH RePORTER |
What this research studies
This research focuses on enhancing the healing process of the tendon-to-bone interface following rotator cuff repairs, which are common yet challenging surgeries. The team aims to develop innovative biomimetic scaffolds that mimic the natural structure of healthy tendon attachments, potentially leading to better recovery outcomes. By utilizing advanced materials and techniques, the project seeks to create solutions that can improve the integration of repaired tendons with bone, thereby reducing failure rates. Patients may benefit from improved surgical outcomes and restored shoulder function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who are undergoing surgical repair for rotator cuff tears.
Not a fit: Patients with rotator cuff injuries who are not candidates for surgical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for rotator cuff injuries, resulting in better recovery and reduced need for additional surgeries.
How similar studies have performed: Previous research has shown promise in using biomimetic approaches for tissue engineering, indicating potential for success in this novel application.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Thomopoulos, Stavros — Columbia University Health Sciences
- Study coordinator: Thomopoulos, Stavros
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.