Improving healing of Achilles tendon injuries
Modifying muscle remodeling following Achilles tendon ruptures
['FUNDING_CAREER'] · UNIVERSITY OF PENNSYLVANIA · NIH-10788380
This study is looking at how muscles and tendons heal after an Achilles tendon injury, using small animals to learn more about the healing process, so we can create better treatments to help people recover faster and feel better.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10788380 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how muscle and tendon healing occurs after an Achilles tendon rupture. Using small animal models, the team will investigate the biological mechanisms that influence muscle-tendon remodeling and function. The goal is to develop optimized treatment strategies that can be tested in clinical trials, ultimately aiming to enhance recovery and improve patient outcomes. The research involves advanced techniques such as ultrasound imaging and muscle physiology assessments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an Achilles tendon rupture and are seeking innovative treatment options.
Not a fit: Patients with chronic tendon injuries or those who have not sustained an Achilles tendon rupture may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better recovery strategies for patients with Achilles tendon injuries, improving their mobility and quality of life.
How similar studies have performed: Previous research in tendon healing and biomechanics has shown promising results, indicating that this approach could yield significant advancements in treatment.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAXTER, JOSH — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: BAXTER, JOSH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.