Improving healing for complex limb injuries
Regenerative engineering for complex extremity trauma
['FUNDING_R01'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-11243754
This study is exploring new ways to help people with serious limb injuries heal better by using special materials and exercise to support the recovery of both muscle and bone, which could mean fewer surgeries and a quicker return to normal activities.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON HEALTH & SCIENCE UNIVERSITY (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-11243754 on ClinicalTrials.gov |
What this research studies
This research focuses on developing new regenerative therapies for patients with severe limb injuries that involve both muscle and bone damage. The approach combines advanced materials that mimic natural tissue structures with exercise to enhance healing. By using nanoscale patterns to guide cell behavior, the research aims to improve the recovery of both muscle and bone, potentially reducing the need for multiple surgeries and long-term rehabilitation. Patients may benefit from a more effective treatment that addresses the complexities of their injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from complex lower extremity trauma involving both muscle and bone injuries.
Not a fit: Patients with isolated injuries to either muscle or bone, without the other being affected, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for severe limb injuries, improving recovery times and outcomes for patients.
How similar studies have performed: Previous research has shown promising results using similar regenerative approaches, indicating potential for success in this area.
Where this research is happening
PORTLAND, UNITED STATES
- OREGON HEALTH & SCIENCE UNIVERSITY — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NAKAYAMA, KARINA — OREGON HEALTH & SCIENCE UNIVERSITY
- Study coordinator: NAKAYAMA, KARINA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.