Improving healing after injuries to skin and gut
Official title: Inhibition of regeneration restraining pathways to promote healing
Funded at Johns Hopkins University · NIH-11129968 · Data updated 2026-11-12
This study is looking at how the body's natural reactions to injuries in places like your skin and gut can sometimes make healing take longer, and the researchers want to find ways to speed up recovery so that patients can heal better after injuries or infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | May 12, 2025 |
| Project end | February 28, 2030 |
| Funding year | 2025 |
| Award (this year) | $649,391 |
| NIH project number | 1R01AR083822-01A1 |
| Project ID | NIH-11129968 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with slow-healing wounds or injuries to the skin or gut.
✕Less likely to help
Patients with injuries that heal normally or those with conditions unrelated to epithelial tissue injuries may not benefit from this research.
What this research studies
This research investigates how certain natural responses to injury in epithelial tissues, like skin and gut, can actually slow down the healing process. The team aims to identify the mechanisms that restrain healing and explore ways to inhibit these pathways. By doing so, they hope to develop new therapies that can enhance regeneration after injuries or infections. Patients may benefit from improved healing outcomes through innovative treatments derived from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve healing after injuries or infections.
How similar studies have gone: Other research has shown promise in targeting healing pathways, suggesting that this approach could yield significant advancements.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Garza, Luis Andres — Johns Hopkins University
- Study coordinator: Garza, Luis Andres
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.