Improving gut health in people with HIV
New Strategy to Improve Gastrointestinal Health in SIV/HIV
This study is looking at how HIV impacts the gut and causes inflammation, and it aims to find ways to help heal the gut and improve health for people living with HIV, no matter their viral load.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10437849 on NIH RePORTER |
What this research studies
This research investigates how HIV affects the gastrointestinal (GI) tract, leading to inflammation and immune system issues. It aims to develop strategies to repair the intestinal barrier, which is crucial for preventing disease progression and associated health problems in individuals living with HIV. The study will test various interventions to see if they can effectively control chronic inflammation and improve overall gut health, regardless of viral load. By focusing on the GI tract, the research seeks to address a significant aspect of HIV management that is often overlooked.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with HIV who are experiencing gastrointestinal issues or related comorbidities.
Not a fit: Patients who are not living with HIV or those without gastrointestinal complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved gastrointestinal health and better overall outcomes for patients living with HIV.
How similar studies have performed: Previous research has shown promise in addressing gastrointestinal health in HIV patients, but this approach focuses specifically on repairing the mucosal barrier, which is relatively novel.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Apetrei, Cristian — University of Pittsburgh at Pittsburgh
- Study coordinator: Apetrei, Cristian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.