Improving growth and brain development in preterm infants through better human milk fortification

Targeting human milk fortification to improve preterm infant growth and brain development

['FUNDING_R01'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10661624

This study is looking at ways to make human milk even better for very premature babies in the NICU, so they can grow strong and develop their brains properly, helping them have a healthier future.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBRIGHAM AND WOMEN'S HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10661624 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the nutritional content of human milk to support the growth and brain development of very preterm infants in neonatal intensive care units (NICUs). It aims to address the issue of undernutrition during critical periods of brain growth by developing more effective human milk fortification strategies. The study will evaluate the impact of these fortified diets on the long-term neurodevelopmental outcomes of preterm infants, who are particularly vulnerable to growth restrictions. By ensuring that these infants receive adequate nutrients, the research seeks to improve their overall health and development.

Who could benefit from this research

Good fit: Ideal candidates for this research are very preterm infants who are receiving care in a neonatal intensive care unit.

Not a fit: Patients who are not preterm or those who are not receiving human milk in the NICU may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved growth and cognitive outcomes for preterm infants, reducing the risk of neurodevelopmental impairments.

How similar studies have performed: Previous research has shown that improved nutritional strategies in NICUs can positively impact the growth and development of preterm infants, suggesting that this approach has potential for success.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.