Improving Glioblastoma Tumor Mapping with MRI
Radiomic spatial maps for identifying viable tumor extent on multi-parametric MRI for Glioblastoma
['FUNDING_R01'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-11095959
This project is developing new MRI mapping techniques to more accurately find glioblastoma tumor areas for better treatment planning.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-11095959 on ClinicalTrials.gov |
What this research studies
Glioblastoma tumors are tricky because they often spread beyond what doctors can easily see on standard MRI scans, which can make treatment planning difficult and lead to the tumor coming back. It's also hard to tell if changes on an MRI after treatment are a returning tumor or just side effects from previous therapies. This project is developing advanced computer-generated 'Radiomic-Image' maps from MRI scans. These maps are designed to precisely highlight the full extent of the tumor, including areas that are hard to spot otherwise. This improved mapping could help doctors plan more effective surgeries and radiation treatments, and better distinguish between tumor recurrence and treatment-related changes.
Who could benefit from this research
Good fit: Patients with glioblastoma who are undergoing treatment planning or monitoring for recurrence would be the primary beneficiaries of this research.
Not a fit: Patients without glioblastoma or those not undergoing MRI-based treatment planning would not directly benefit from this specific imaging technology.
Why it matters
Potential benefit: If successful, this work could lead to more precise treatment for glioblastoma patients, potentially reducing recurrence and improving outcomes.
How similar studies have performed: The initial version of the Radiomic-Image map has shown promise, suggesting this approach has a foundation for further development.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TIWARI, PALLAVI — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: TIWARI, PALLAVI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.