Improving glaucoma detection using advanced imaging technology
Official title: Advancing visible light optical coherence tomography in glaucoma detection
Funded at Johns Hopkins University · NIH-11072978 · Data updated 2026-11-12
This study is testing a new imaging technique to help doctors spot early signs of glaucoma more clearly, which could lead to better treatments for patients with this eye condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $436,721 |
| NIH project number | 5R01EY034607-03 |
| Project ID | NIH-11072978 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for glaucoma or those in the early stages of the disease.
✕Less likely to help
Patients with advanced glaucoma or those who do not have any signs of glaucoma may not benefit from this research.
What this research studies
This research focuses on enhancing the detection of early glaucoma damage through a new imaging technique called visible light optical coherence tomography (VIS-OCT). By developing a second-generation VIS-OCT device, the researchers aim to improve image quality and resolution, allowing for more accurate identification of glaucoma in its early stages. The study will also investigate how oxygen consumption in the macula relates to the severity of glaucoma, potentially leading to better treatment options. Patients will be monitored using advanced imaging markers to assess their condition more effectively.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of glaucoma, preserving vision and improving quality of life for patients.
How similar studies have gone: Previous studies have shown promising results with similar imaging techniques, indicating potential for success in this novel approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Yi, Ji — Johns Hopkins University
- Study coordinator: Yi, Ji
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.