Improving genetic understanding of diabetes risk in Native Hawaiians
Leveraging the Evolutionary History to Improve Identification of Trait-Associated Alleles and Risk Stratification Models in Native Hawaiians
This study is looking at how genetics might play a role in the high rates of obesity and diabetes among Native Hawaiians, with the goal of finding better ways to prevent and treat these conditions specifically for this community.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10906789 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors that contribute to high rates of obesity and diabetes among Native Hawaiians, a population that has been largely overlooked in genetic studies. By examining the evolutionary history of Native Hawaiians, the research aims to identify specific genetic traits associated with these health conditions. The project will utilize advanced genomic techniques and integrate population genetics with epidemiological data to create a comprehensive model for risk stratification. This approach seeks to provide insights that could lead to more effective prevention and treatment strategies tailored to this unique population.
Who could benefit from this research
Good fit: Ideal candidates for this research are Native Hawaiians who are at risk for or currently experiencing obesity and diabetes.
Not a fit: Patients who are not of Native Hawaiian descent or those without a family history of obesity or diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification of genetic risk factors for diabetes and obesity, ultimately enhancing health outcomes for Native Hawaiians.
How similar studies have performed: While there has been some success in genetic studies focusing on other ethnic groups, this approach specifically targeting Native Hawaiians is relatively novel and underexplored.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Chiang, Charleston — University of Southern California
- Study coordinator: Chiang, Charleston
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.