Improving genetic testing for families at risk of Lynch syndrome
Official title: Let's Talk: Overcoming barriers to the uptake of cascade screening through a stakeholder-informed online intervention
Funded at Univ of North Carolina Chapel Hill · NIH-10808230 · Data updated 2026-11-12
This study is creating an easy-to-use online tool called 'Let's Talk' to help families with Lynch syndrome get the support and information they need for cancer screening, making it simpler for them to communicate and plan for genetic testing.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 20, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $575,098 |
| NIH project number | 1R21HG013417-01 |
| Project ID | NIH-10808230 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with Lynch syndrome and their first-degree relatives who may benefit from cascade screening.
✕Less likely to help
Patients who do not have a family history of Lynch syndrome or those who are not first-degree relatives may not receive any benefit from this research.
What this research studies
This research focuses on enhancing cascade screening for Lynch syndrome, a genetic condition that increases cancer risk among family members. It aims to develop an interactive online intervention called 'Let's Talk' that addresses barriers to screening by providing tailored information and support for patients and their families. The approach involves engaging stakeholders to create a user-friendly platform that facilitates communication and planning for genetic testing. By adapting a previously successful paper-based intervention into an online format, the project seeks to improve accessibility and ongoing support for families affected by Lynch syndrome.
Why it matters
Potential benefit: If successful, this research could significantly increase the number of family members screened for Lynch syndrome, leading to earlier cancer detection and prevention.
How similar studies have gone: Previous research has shown success with similar interventions in promoting genetic testing and screening, indicating a promising approach for this project.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Roberts, Megan C. — Univ of North Carolina Chapel Hill
- Study coordinator: Roberts, Megan C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.