Improving fracture healing in older adults
RR&D Research Career Scientist Award Application
This study is looking at a new way to help older adults heal better from fractures by using a special protein, and it aims to make recovery easier and improve their overall quality of life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rlr VA Medical Center NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10897878 on NIH RePORTER |
What this research studies
This research focuses on developing new therapies to enhance the healing of fractures, particularly in older adults. The team is investigating how a specific protein, Sirtuin-1, can be activated to improve healing outcomes, reduce pain, and enhance mobility. By conducting laboratory studies and translating findings into clinical applications, the researchers aim to provide better treatment options for patients suffering from fractures. The ultimate goal is to improve the quality of life for both veterans and civilians who experience fractures.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those aged 65 and above, who have experienced fractures.
Not a fit: Patients who are younger than 65 or do not have fractures may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective healing of fractures in older adults, reducing pain and improving mobility.
How similar studies have performed: Previous research has shown promise in targeting Sirtuin-1 for improving healing outcomes, indicating potential success for this approach.
Where this research is happening
Indianapolis, United States
- Rlr VA Medical Center — Indianapolis, United States (Active)
Researchers
- Principal investigator: Kacena, Melissa a — Rlr VA Medical Center
- Study coordinator: Kacena, Melissa a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.