Improving fluoride treatment for root cavities in older adults
Enhancing the effect of fluoride for root caries control in high-risk older adults (Resub)
This study is looking at a new way to make fluoride work better for preventing tooth decay in older adults, especially those who might be more at risk due to health issues or medications, by using tiny fluoride particles that can better protect their teeth.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10850549 on NIH RePORTER |
What this research studies
This research focuses on enhancing the effectiveness of fluoride in preventing root caries, particularly in older adults who are at higher risk due to factors like systemic health issues and medication side effects. The study aims to develop a new therapy using fluoride nanoparticles that significantly improve fluoride's ability to penetrate and protect vulnerable tooth surfaces. By addressing the limitations of current fluoride treatments, this research seeks to provide a more effective solution for maintaining oral health in the aging population.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who are at high risk for root caries due to health conditions or medications.
Not a fit: Patients under 65 years of age or those without risk factors for root caries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention of root caries, improving oral health and quality of life for older adults.
How similar studies have performed: Previous studies have shown promising results with nanoparticle applications in dental treatments, suggesting potential for success in this novel approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Andalo-Tenuta, Livia Maria — University of Michigan at Ann Arbor
- Study coordinator: Andalo-Tenuta, Livia Maria
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.