Improving fluid management in sepsis treatment

Precision Guidance of Resuscitation and Deresuscitation in Sepsis

NIH-funded research Daxor Corporation · NIH-10602712

This study is looking at how to improve fluid treatment for people with sepsis by using a special device to measure blood volume, so that each patient gets just the right amount of fluids they need, which could help them recover better.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionDaxor Corporation NIH-funded
Lab location1 site (Oak Ridge, United States)
Project IDNIH-10602712 on NIH RePORTER

What this research studies

This research investigates how to better manage fluid resuscitation in patients with sepsis, a serious condition that affects millions. It challenges the traditional approach of administering large amounts of fluids based on general guidelines, instead focusing on precise measurements of blood volume using advanced technology. By utilizing Daxor’s BVA-100 device, the study aims to tailor fluid treatment to individual patients' needs, potentially leading to better outcomes. The research will involve a randomized controlled trial to assess the effectiveness of this personalized approach.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing sepsis or septic shock.

Not a fit: Patients who are not critically ill or do not have sepsis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer fluid management strategies for patients with sepsis.

How similar studies have performed: Previous studies have shown promising results with personalized fluid management approaches in critically ill patients, indicating potential for success in this research.

Where this research is happening

Oak Ridge, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.