Improving flu vaccines for older adults with existing immunity

Seasonal and universal Vaccination in aged populations with pre-existing immunity

NIH-funded research Georgia State University · NIH-11076676

This study is looking for ways to make flu shots work better for older adults who might already have some immunity, by creating a new type of vaccine that helps boost their protection against different flu strains.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia State University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-11076676 on NIH RePORTER

What this research studies

This research investigates how to enhance the effectiveness of flu vaccinations in older adults who may already have some level of immunity. It focuses on developing new vaccine strategies that can provide better cross-protection against various flu strains. The approach includes creating a multi-target vaccine that combines different components to stimulate a stronger immune response. By understanding the role of pre-existing immunity, the research aims to improve vaccination outcomes for the elderly population.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 65 and older who may have received previous flu vaccinations.

Not a fit: Patients under the age of 65 or those without any prior flu vaccinations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective flu vaccines that better protect older adults from influenza.

How similar studies have performed: Previous research has shown promise in developing multi-target vaccines, but this specific approach for older adults remains largely untested.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.