Improving flexible thinking and learning for individuals with autism

Intervention-induced plasticity of flexibility and learning mechanisms in ASD

NIH-funded research Children's Research Institute · NIH-11175401

This project explores how interventions can help children and young adults with autism spectrum disorder better use what they learn in new situations.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionChildren's Research Institute NIH-funded
Lab location1 site (Washington, United States)
Project IDNIH-11175401 on NIH RePORTER

What this research studies

Many individuals with autism find it hard to apply skills learned in one setting to different real-world situations. This project aims to understand why this happens by looking at how learning and flexible thinking are connected in the brain. Researchers will use brain imaging and behavioral tests to see if teaching more flexible behaviors can change how individuals with autism learn. The goal is to discover how the brain generates new ideas versus remembering specific examples, which could lead to better ways to help individuals generalize their skills.

Who could benefit from this research

Good fit: Ideal candidates for future related studies would likely be children and young adults, aged 0-20 years, diagnosed with autism spectrum disorder.

Not a fit: Patients without autism spectrum disorder or those outside the target age range may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to new interventions that significantly improve real-world outcomes and the ability to transfer learned knowledge for individuals with autism.

How similar studies have performed: While the challenge of generalization in ASD is known, this specific connection between learning and flexibility has received little attention, suggesting a novel approach.

Where this research is happening

Washington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic Disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.