Improving fitness response to aerobic exercise after operable breast cancer
A Randomized Trial to Minimize Non-Response to Aerobic Training in Operable Breast Cancer
This project tests whether doing more or longer aerobic exercise can help people treated for operable breast cancer improve heart and lung fitness.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11306568 on NIH RePORTER |
What this research studies
You would be randomly assigned to different amounts and lengths of supervised aerobic exercise to see which approach helps more people increase their cardiorespiratory fitness. The team will measure fitness before and after the program, track longer-term fitness and health, and collect information about what helped or got in the way of doing the exercise. This R37 extension builds on a parent trial and focuses on people who did not respond to standard exercise doses to learn how to reduce non-response. The goal is to better tailor exercise prescriptions for breast cancer survivors.
Who could benefit from this research
Good fit: Adults treated for operable (early-stage) breast cancer who are medically cleared to participate in aerobic exercise are the intended participants.
Not a fit: People with metastatic disease, those who cannot safely perform aerobic exercise due to serious cardiac or other health issues, or those who already have very high fitness may not benefit from this program.
Why it matters
Potential benefit: If successful, the work could help more breast cancer survivors raise their fitness levels and lower long-term risk of heart disease.
How similar studies have performed: Prior exercise trials improved fitness for some but showed many non-responders, so extending exercise length and volume is promising but not yet proven to solve that problem.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Scott, Jessica — Sloan-Kettering Inst Can Research
- Study coordinator: Scott, Jessica
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.