Improving fitness in children with single ventricle heart conditions through exercise.
RE-ENERGIZE FONTAN - RandomizEd Exercise INtERvention desiGned to MaximIZE Fitness in Pediatric FONTAN patients
This study is looking to help kids who have had Fontan surgery feel stronger and healthier by trying out a special exercise program to see how it can improve their fitness and overall health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10775765 on NIH RePORTER |
What this research studies
This research focuses on enhancing the physical fitness of pediatric patients who have undergone Fontan surgery, a procedure for those with single ventricle heart conditions. The study aims to implement a structured exercise program to assess its effects on exercise capacity, muscle mass, and overall health outcomes. By monitoring changes in muscle function and mitochondrial activity, the research seeks to understand how exercise can mitigate the risks associated with long-term complications in these patients. Participants will engage in tailored exercise interventions designed to improve their physical well-being and potentially reduce morbidity and mortality rates.
Who could benefit from this research
Good fit: Ideal candidates for this research are pediatric patients aged 0-21 years who have undergone Fontan palliation.
Not a fit: Patients who do not have a history of Fontan surgery or those with other severe comorbidities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life and longevity for children with Fontan physiology.
How similar studies have performed: Previous limited studies have shown that exercise interventions are safe and effective in children with congenital heart disease, suggesting potential for success in this targeted approach.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Selamet Tierney, Elif Seda — Stanford University
- Study coordinator: Selamet Tierney, Elif Seda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.