Improving fatigue management for women with metastatic breast cancer

Adaptation and Preliminary Evaluation of Energize-MBC: Cognitive Behavioral Therapy for Fatigue among Women with Metastatic Breast Cancer

NIH-funded research H. Lee Moffitt Cancer Ctr & Res Inst · NIH-10873532

This study is testing a new online therapy program called Energize-MBC designed to help women with metastatic breast cancer who feel tired from their treatment, making it easier for them to feel better and enjoy their daily lives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionH. Lee Moffitt Cancer Ctr & Res Inst NIH-funded
Lab location1 site (Tampa, United States)
Project IDNIH-10873532 on NIH RePORTER

What this research studies

This research focuses on adapting a cognitive behavioral therapy program specifically for women with metastatic breast cancer who experience fatigue due to treatment with CDK4/6 inhibitors. The program, called Energize-MBC, aims to enhance the quality of life for these patients by addressing their unique needs. The approach includes refining a web-based platform for delivering therapy via telemedicine, making it accessible and convenient. The study will evaluate how feasible and acceptable this adapted therapy is, as well as its preliminary effectiveness in reducing fatigue and improving daily functioning.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with metastatic breast cancer who are currently receiving treatment with CDK4/6 inhibitors.

Not a fit: Patients who do not have metastatic breast cancer or are not undergoing treatment with CDK4/6 inhibitors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce fatigue and improve the quality of life for women living with metastatic breast cancer.

How similar studies have performed: Previous research has shown that cognitive behavioral therapy can effectively reduce fatigue in cancer patients, suggesting that this adapted approach may also be beneficial.

Where this research is happening

Tampa, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast Cancer PatientCancer CenterCancer InterventionCancer PatientCancer Survivor
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.