Improving fatigue and quality of life in older men with cancer and low testosterone
Improving cancer-related fatigue, sexual dysfunction and quality of life in older men with cancer and androgen deficiency
This study is looking at how testosterone replacement therapy might help older men with cancer feel less tired, improve their sex life, and boost their overall quality of life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Inst for Biomedical/clinical Res NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10861052 on NIH RePORTER |
What this research studies
This research investigates how testosterone replacement therapy can alleviate cancer-related fatigue, sexual dysfunction, and improve overall quality of life in older men diagnosed with cancer. The study aims to assess the effectiveness of this therapy, particularly in patients experiencing significant fatigue, which is common among those undergoing cancer treatments. By focusing on older men, the research seeks to address a critical gap in treatment options for this demographic, as current FDA-approved solutions for cancer-related fatigue are lacking. Participants will be monitored for improvements in their physical function and well-being throughout the study.
Who could benefit from this research
Good fit: Ideal candidates for this research are older men aged 65 and above who are diagnosed with cancer and experiencing symptoms of fatigue and sexual dysfunction.
Not a fit: Patients who are younger than 65 or those without cancer or testosterone deficiency may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option that significantly enhances the quality of life for older men suffering from cancer-related fatigue and associated symptoms.
How similar studies have performed: Previous clinical trials have shown success in using testosterone replacement therapy for improving quality of life in non-cancer older men, but this specific application for cancer-related fatigue is novel.
Where this research is happening
Seattle, United States
- Seattle Inst for Biomedical/clinical Res — Seattle, United States (Active)
Researchers
- Principal investigator: Garcia, Jose M. — Seattle Inst for Biomedical/clinical Res
- Study coordinator: Garcia, Jose M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.