Improving fat grafts for breast reconstruction
Official title: A recombinant matrix to improve autologous tissue grafts
Funded at Insoma Bio, INC. · NIH-10652973 · Data updated 2026-11-12
This study is working on a new way to make fat grafting for breast reconstruction after cancer treatment even better, so that it can be a safer and more effective option than traditional breast implants.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Insoma Bio, INC. NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | September 11, 2019 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,035,879 |
| NIH project number | 5R44CA244110-03 |
| Project ID | NIH-10652973 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are breast cancer survivors seeking reconstructive surgery who prefer alternatives to implants.
✕Less likely to help
Patients who do not have sufficient fat tissue available for grafting or those who are not undergoing breast reconstruction may not benefit from this research.
What this research studies
This research focuses on developing a new tissue matrix that enhances the effectiveness of autologous fat grafting in breast reconstructive surgery. The goal is to provide a safer and more accessible alternative to traditional breast implants, which have raised concerns regarding long-term health effects. By addressing the limitations of current fat grafting techniques, this project aims to improve the outcomes for patients undergoing breast reconstruction after cancer treatment. The approach involves refining the methods of fat harvesting and grafting to ensure better structural integrity and usability of the fat tissue.
Why it matters
Potential benefit: If successful, this research could provide breast cancer patients with a safer and more effective option for breast reconstruction.
How similar studies have gone: Previous studies have shown promise in improving fat grafting techniques, but this specific approach is innovative and aims to address existing challenges in the field.
Where this research is happening
-
Insoma Bio, INC.
Durham, United States Active
Researchers
- Principal investigator: Roberts, Stefan — Insoma Bio, INC.
- Study coordinator: Roberts, Stefan
Related research
Other NIH-funded projects on the same topics.
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Improving recovery from peripheral nerve injuries with a new injectable material
This study is looking at a new injectable treatment called Fractomer that could help people heal better after injuries to their peripheral nerves, which can cause pain and disability.
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Developing a new alternative to fat transfer for repairing soft tissue
This study is working on a new, easy-to-use solution for repairing soft tissue that could help people needing reconstruction in places like the face, breasts, or arms, without the need for invasive fat grafting procedures.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.