Improving exercise testing and physical activity assessment in children with health conditions.

Transforming Exercise Testing and Physical Activity Assessment in Children: New Approaches to Advance Clinical Translational Research in Child Health

NIH-funded research University of California-Irvine · NIH-10450177

This study is looking to improve how we measure exercise and physical activity in kids, especially those with sickle cell disease, by creating better testing methods that match their everyday activities and using new technology to understand their health better.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-10450177 on NIH RePORTER

What this research studies

This research focuses on enhancing how exercise testing and physical activity are assessed in children, particularly those with conditions like sickle cell disease. It aims to develop new testing protocols that reflect real-life activity patterns and utilize advanced technologies for better data analysis. By addressing current limitations in clinical research applications, the project seeks to provide deeper insights into children's health and disease mechanisms. The research will also tackle logistical challenges to facilitate multicenter studies, ensuring a broader impact on child health.

Who could benefit from this research

Good fit: Ideal candidates for this research include children aged 0-21, particularly those diagnosed with sickle cell disease or cystic fibrosis.

Not a fit: Patients with acute illnesses or those outside the age range of 0-21 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved assessment and management of physical activity in children with chronic health conditions, enhancing their overall health outcomes.

How similar studies have performed: Previous research has shown promise in using advanced exercise testing methods in pediatric populations, suggesting potential for success in this novel approach.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Hb SS diseaseHbSS diseaseHemoglobin S DiseaseHemoglobin sickle cell diseaseHemoglobin sickle cell disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.