Improving exercise in adolescents with pulmonary arterial hypertension using mobile health technology
Official title: MhOVE-PPH Study: Mobile health interventiOn to improVe Exercise in Pediatric PH
Funded at Vanderbilt University Medical Center · NIH-11075230 · Data updated 2026-11-12
This study is all about helping teenagers with pulmonary arterial hypertension (PAH) get more active by using a fun mobile app that tracks their steps and offers personal coaching to encourage them to exercise more over 12 weeks, making it easier for them to feel better and enjoy life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $260,614 |
| NIH project number | 5R34HL173389-02 |
| Project ID | NIH-11075230 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 0-21 years diagnosed with pulmonary arterial hypertension.
✕Less likely to help
Patients who are not diagnosed with pulmonary arterial hypertension or are outside the age range of 0-21 years may not benefit from this research.
What this research studies
This research focuses on enhancing physical activity in adolescents suffering from pulmonary arterial hypertension (PAH) through a mobile health intervention. The approach involves real-time activity tracking combined with personalized behavioral coaching to encourage increased exercise levels. By utilizing technology, the study aims to provide a scalable and cost-effective solution to improve exercise capacity and quality of life for young patients. Participants will engage in a 12-week program designed to motivate them to increase their daily steps and overall physical activity.
Why it matters
Potential benefit: If successful, this research could significantly improve the exercise capacity and quality of life for adolescents with pulmonary arterial hypertension.
How similar studies have gone: Previous research has shown success with mobile health interventions in adult PAH populations, indicating potential for similar outcomes in adolescents.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Austin, Eric Douglas — Vanderbilt University Medical Center
- Study coordinator: Austin, Eric Douglas
Related research
Other NIH-funded projects on the same topics.
-
Improving healthcare for patients with inherited cancer syndromes using a web-based platform
This study is testing a new online tool called MeTree that helps people understand their risk for inherited cancer by combining their medical records and family health history, making it easier for patients and doctors to get the information they need for better care and support.
-
Stroke prevention with hydroxyurea for children with sickle cell anemia in Nigeria
A multinational, patient-facing study tests whether hydroxyurea can safely prevent first strokes in Nigerian children with sickle cell anemia.
-
Scaling Up Task-Shifted Epilepsy Care for Children in Africa
A study to help children with epilepsy in Africa get diagnosed and receive seizure care through trained community health workers.
-
Enhanced surveillance for new vaccine‑preventable diseases
A Vanderbilt team is tracking how well vaccines work and how diseases like flu, RSV, norovirus, and SARS‑CoV‑2 affect young children over time.
-
Generative AI to create private, fair health data for research
A researcher at Vanderbilt aims to use Generative AI to create synthetic health data that protects patient privacy while helping AI models be fairer and more accurate.
-
ConProject-003: A patient-facing initiative at Vanderbilt for advancing care
A Vanderbilt-led project (ConProject-003) is funded to drive improvements in care for people with a specific health condition through a dedicated program.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.