NIH-funded research R01 grant

Improving exercise and fitness in older adults with cardiovascular disease.

Official title: Optimizing Aerobic Fitness and Functional Response to Exercise in Older Adults.

Funded at University of Vermont & St Agric College · NIH-10775114 · Data updated 2026-11-12

This study is looking at how different types of exercise can help older adults with heart issues get stronger and feel better, by comparing moderate workouts to more intense interval training, so they can find the best way to improve their fitness and everyday activities.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Vermont & St Agric College
NIH-funded
Lab location1 site (Burlington, United States)
Project startJuly 15, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$625,835
NIH project number1R01AG084636-01
Project IDNIH-10775114 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults, particularly those with cardiovascular disease who have experienced physical disability due to hospitalization.

Less likely to help

Patients who are not older adults or those without cardiovascular disease may not benefit from this research.

What this research studies

This research focuses on enhancing aerobic fitness and functional responses to exercise in older adults, particularly those affected by cardiovascular disease. It aims to compare the effectiveness of different exercise training methods, including moderate intensity continuous aerobic training and high intensity interval training, to improve physical capacity and muscle strength. The study will involve older adults participating in tailored exercise programs designed to address the unique challenges they face due to aging and hospitalization. By measuring improvements in physical function and fitness levels, the research seeks to identify the most effective strategies for rehabilitation.

Why it matters

Potential benefit: If successful, this research could lead to improved physical function and quality of life for older adults recovering from cardiovascular disease.

How similar studies have gone: Previous research has shown that high intensity interval training can significantly improve fitness levels in older adults, indicating potential for success in this innovative approach.

Where this research is happening

  • University of Vermont & St Agric College
    Burlington, United States
    Active

Researchers

  • Principal investigator: Khadanga, Sherrie — University of Vermont & St Agric College
  • Study coordinator: Khadanga, Sherrie

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.