Improving executive function in young children with Down syndrome

Executive Function Intervention for Young Children with Down Syndrome

NIH-funded research Colorado State University · NIH-10879710

This study is testing a fun 12-week program called EXPO that helps young children with Down syndrome improve their thinking and problem-solving skills through play, with support from their caregivers to make it just right for each child.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColorado State University NIH-funded
Lab location1 site (Fort Collins, United States)
Project IDNIH-10879710 on NIH RePORTER

What this research studies

This research focuses on enhancing executive function skills in young children with Down syndrome through a caregiver-mediated intervention called EXPO (Executive Function Play Opportunities). The program lasts 12 weeks and is designed to leverage the natural strengths and challenges of children with Down syndrome, making it easier for them to engage in activities that promote cognitive development. By incorporating feedback from caregivers, the intervention aims to be adaptive and personalized, addressing the unique needs of each child. The study will evaluate the effectiveness of this approach in fostering better developmental outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are young children aged 0-11 years diagnosed with Down syndrome and their caregivers.

Not a fit: Patients who are older than 11 years or do not have a diagnosis of Down syndrome may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved cognitive and behavioral skills in young children with Down syndrome, enhancing their overall development and quality of life.

How similar studies have performed: Previous research has shown promising results with similar caregiver-mediated interventions aimed at enhancing cognitive skills in children with developmental delays.

Where this research is happening

Fort Collins, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.