Improving epilepsy diagnosis with an automated EEG risk score

EpiScalp: An EEG Analytics Solution to Improve Diagnosis of Epilepsy

['FUNDING_SBIR_2'] · NEUROLOGIC SOLUTIONS, INC. · NIH-11168672

This project will use an automated EEG tool called EpiScalp that produces a 0–1 risk score from 10–20 minutes of scalp EEG to help people with suspected seizures get a clearer epilepsy diagnosis.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorNEUROLOGIC SOLUTIONS, INC. (nih funded)
Locations1 site (MCLEAN, UNITED STATES)
Trial IDNIH-11168672 on ClinicalTrials.gov

What this research studies

EpiScalp is an EEG analytics algorithm that analyzes short routine scalp EEG recordings and outputs a 0–1 risk score for epilepsy. The team will further develop the software to better recognize epileptiform signals and to distinguish them from artifacts that can mimic seizures. They plan to validate the tool using clinical EEG recordings and compare its results to standard visual EEG review by clinicians. The goal is to reduce delays and errors in diagnosis so patients spend less time on incorrect treatments or unnecessary testing.

Who could benefit from this research

Good fit: Ideal candidates are people with unexplained spells or suspected seizures who are undergoing routine scalp EEG recording.

Not a fit: People whose epilepsy diagnosis is already firmly established by other tests, those monitored only with implanted intracranial EEG, or people with conditions that do not produce visible scalp EEG changes may not benefit.

Why it matters

Potential benefit: If successful, EpiScalp could reduce epilepsy misdiagnosis, avoid unnecessary antiseizure medications, and speed patients to appropriate treatment.

How similar studies have performed: Previous automated EEG and machine-learning tools have shown promise at detecting epileptiform activity but have not yet eliminated high misdiagnosis rates, so this work builds on promising but still-imperfect approaches.

Where this research is happening

MCLEAN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.