Improving emergency responses to opioid overdoses

Developing and testing the Opioid Rapid Response System

NIH-funded research Real Prevention, LLC · NIH-10872315

This study is working on a new system to help everyday people quickly respond to opioid overdoses by training them to use naloxone, a lifesaving medication, and connecting them through an app so they can get help to those in need faster, no matter where they are.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionReal Prevention, LLC NIH-funded
Lab location1 site (Clifton, UNITED STATES)
Project IDNIH-10872315 on NIH RePORTER

What this research studies

This research focuses on developing the Opioid Rapid Response System (ORRS) to enhance the effectiveness of emergency responses to opioid overdoses. It aims to create innovative recruitment and training strategies for lay citizen responders who can administer naloxone, a life-saving medication for overdose situations. The project will utilize existing apps like PulsePoint to connect these responders with overdose events in real-time, ensuring timely assistance in both urban and rural settings. By addressing the challenges of rapid response, this initiative seeks to save lives and reduce the impact of opioid overdoses.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals living in communities with high rates of opioid overdoses, as well as those interested in becoming trained responders.

Not a fit: Patients who do not reside in areas affected by opioid overdoses or who are not interested in participating in training programs may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve survival rates for individuals experiencing opioid overdoses by ensuring timely access to life-saving interventions.

How similar studies have performed: Previous initiatives using similar community-based response systems, such as PulsePoint for cardiac events, have shown success, indicating potential for this approach in addressing opioid overdoses.

Where this research is happening

Clifton, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.