Improving emergency care for children with sickle cell disease

Sickle Cell Improvement: ENhancing Care in the Emergency Department (SCIENCE)

NIH-funded research Nemours Children's Hospital, Delaware · NIH-10896246

This study is working to make sure kids with sickle cell disease get better and faster care in the emergency room when they're in pain, so they can feel better sooner and stay out of the hospital more often.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionNemours Children's Hospital, Delaware NIH-funded
Lab location1 site (Wilmington, United States)
Project IDNIH-10896246 on NIH RePORTER

What this research studies

This research focuses on enhancing the emergency department care for children suffering from sickle cell disease, a condition that causes severe pain crises. It aims to implement a care pathway that adheres to established pain management guidelines, which are often not followed due to various barriers, including structural racism. By using multifaceted strategies, the project seeks to improve the timeliness and quality of care these children receive during acute pain episodes. The ultimate goal is to reduce hospitalizations and improve the overall health outcomes for affected children.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with sickle cell disease and experience acute pain crises.

Not a fit: Patients who do not have sickle cell disease or are outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to faster and more effective pain management for children with sickle cell disease, significantly improving their quality of life.

How similar studies have performed: Previous research has shown that implementing structured pain management protocols can improve outcomes for patients with sickle cell disease, indicating that this approach has potential for success.

Where this research is happening

Wilmington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Blood Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.