Improving electrode placement for epilepsy treatment using brain imaging techniques
Optimized Intracranial EEG Targeting in Focal Epilepsy based upon Neuroimaging Connectomics
This study is looking for ways to improve epilepsy treatment by using advanced imaging techniques to help doctors place electrodes more accurately in the brain, so they can better predict and manage seizures for patients who are having trouble with their epilepsy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11042770 on NIH RePORTER |
What this research studies
This research aims to enhance the treatment of intractable epilepsy by developing methods to better target the placement of electrodes used in intracranial EEG (IEEG) procedures. By integrating noninvasive MRI imaging with IEEG data, the study seeks to create tools that can accurately map brain networks associated with seizures. Patients undergoing IEEG will be involved in testing how well these imaging techniques can predict seizure onset and propagation, ultimately aiming to improve surgical outcomes. The approach focuses on validating biomarkers derived from neuroimaging to guide clinical decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with intractable epilepsy who are being evaluated for surgical intervention.
Not a fit: Patients with epilepsy that is well-controlled by medication or those who are not candidates for surgical evaluation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and less invasive treatment options for patients with epilepsy.
How similar studies have performed: Previous research has shown promise in using neuroimaging techniques to inform surgical approaches in epilepsy, indicating that this approach has potential for success.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Davis, Kathryn Adamiak — University of Pennsylvania
- Study coordinator: Davis, Kathryn Adamiak
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.