Improving electrical stimulation treatments for epilepsy
Optimization and mechanisms of electrical neurostimulation in mouse models of epilepsy
['FUNDING_CAREER'] · WASHINGTON UNIVERSITY · NIH-10992162
This study is looking at how to make electrical treatments for epilepsy work better for people whose seizures don't respond to medication, using mice to find the best ways to stimulate the brain.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10992162 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the effectiveness of electrical neurostimulation therapies for patients with drug-resistant epilepsy. By studying mouse models, the project aims to understand how different stimulation parameters and electrode placements can optimize treatment outcomes. The research will explore the underlying mechanisms of neurostimulation to identify novel therapeutic effects that may alter the course of epilepsy. The principal investigator, Dr. Thomas Foutz, will work under the guidance of experienced mentors to develop skills in this innovative treatment approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from drug-resistant epilepsy who have not found relief from standard treatments.
Not a fit: Patients with well-controlled epilepsy or those who do not have epilepsy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with epilepsy who do not respond to traditional medications.
How similar studies have performed: Previous research has shown promise in using neurostimulation for epilepsy, indicating that this approach has potential for significant advancements in treatment.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FOUTZ, THOMAS — WASHINGTON UNIVERSITY
- Study coordinator: FOUTZ, THOMAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.