Improving ECMO treatment by eliminating the need for blood thinners
ECMO without Anticoagulation
This study is looking at a new way to make ECMO, a life-support system for seriously ill patients, safer by using a special coating that helps prevent blood clots without the need for blood-thinning medications, which can cause bleeding problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11120032 on NIH RePORTER |
What this research studies
This research focuses on enhancing the safety and effectiveness of ECMO, a life-support system used in critical care. It aims to develop a special surface coating that prevents blood clotting without the use of anticoagulants, which can lead to serious bleeding complications. By using a nitric oxide-based coating, the study seeks to reduce the risks associated with traditional anticoagulation methods. Patients on ECMO may benefit from fewer complications and improved outcomes as a result of this innovative approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients requiring ECMO support, particularly those at high risk for bleeding or clotting complications.
Not a fit: Patients who are not candidates for ECMO or those with contraindications to nitric oxide therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce complications related to bleeding and clotting in patients undergoing ECMO treatment.
How similar studies have performed: Previous research has shown promise in using nitric oxide for anticoagulation, suggesting that this approach could lead to significant advancements in ECMO treatment.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Rojas-Pena, Alvaro — University of Michigan at Ann Arbor
- Study coordinator: Rojas-Pena, Alvaro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.