Improving ECG methods to quickly identify heart issues in chest pain patients
Official title: Electrocardiographic Detection of Non-ST Elevation Myocardial Events for Accelerated Classification of Chest Pain Encounters (ECG-SMART 2)
Funded at University of Pittsburgh at Pittsburgh · NIH-10893324 · Data updated 2026-11-12
This study is working on a new tool to help doctors quickly and accurately check patients with chest pain in the emergency room, using advanced technology to spot heart issues that might be missed by regular tests, so they can provide faster and better care for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | April 15, 2018 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $642,178 |
| NIH project number | 5R01HL137761-07 |
| Project ID | NIH-10893324 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who present to emergency departments with chest pain symptoms.
✕Less likely to help
Patients who do not experience chest pain or have already been diagnosed with a stable cardiac condition may not benefit from this research.
What this research studies
This research focuses on enhancing the ability to quickly and accurately assess patients who arrive at emergency departments with chest pain, a serious condition that can indicate heart problems. By utilizing advanced machine learning algorithms on a large database of ECG readings, the project aims to develop tools that can detect non-ST elevation myocardial events, which are often missed by traditional ECG methods. The goal is to create a real-time decision support system that can assist healthcare providers in making faster and more informed decisions at the bedside. This could lead to improved patient outcomes by ensuring timely treatment for those at risk of acute coronary events.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses for patients experiencing chest pain, potentially saving lives.
How similar studies have gone: Previous research has shown promise in using machine learning for ECG interpretation, indicating that this approach could be effective in clinical settings.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Al-Zaiti, Salah S — University of Pittsburgh at Pittsburgh
- Study coordinator: Al-Zaiti, Salah S
Related research
Other NIH-funded projects on the same topics.
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ECG-BASED smart tools to quickly classify chest pain in emergency care
A patient-focused project to use advanced ECG analysis and machine learning to quickly identify heart problems in people with chest pain when they arrive at the ER.
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How emergency doctors’ decisions about chest pain affect testing and outcomes
A study using Medicare data will see if doctors who tend to admit chest-pain patients to the hospital lead to more tests and different outcomes for those patients.
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Using ECGs to find hidden heart attacks in people with chest pain
This project is creating smart ECG tools to quickly spot heart attacks that don't show the classic ST-elevation in people who come to the emergency room with chest pain.
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MACE-Alert: AI tools to help triage chest pain in the emergency department
An AI-powered system and a patient-facing chat tool aim to improve how emergency teams evaluate and triage people with chest pain.
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Electrocardiographic warning system to speed up chest-pain care (ECG-SMART 2)
A research project is testing new ECG-based computer tools to quickly and safely identify patients with potentially serious chest pain in emergency departments.
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Evaluating a new approach for managing chest pain patients in outpatient settings
This study is testing a new way to help people with chest pain who aren't at high risk by letting them go home from the emergency room instead of staying in the hospital, and then checking in with them within three days to make sure they're doing okay and to manage any heart health concerns.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.