NIH-funded research R01 grant

Improving ECG methods to quickly identify heart issues in chest pain patients

Official title: Electrocardiographic Detection of Non-ST Elevation Myocardial Events for Accelerated Classification of Chest Pain Encounters (ECG-SMART 2)

Funded at University of Pittsburgh at Pittsburgh · NIH-10893324 · Data updated 2026-11-12

This study is working on a new tool to help doctors quickly and accurately check patients with chest pain in the emergency room, using advanced technology to spot heart issues that might be missed by regular tests, so they can provide faster and better care for you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startApril 15, 2018
Project endJune 30, 2026
Funding year2024
Award (this year)$642,178
NIH project number5R01HL137761-07
Project IDNIH-10893324 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who present to emergency departments with chest pain symptoms.

Less likely to help

Patients who do not experience chest pain or have already been diagnosed with a stable cardiac condition may not benefit from this research.

What this research studies

This research focuses on enhancing the ability to quickly and accurately assess patients who arrive at emergency departments with chest pain, a serious condition that can indicate heart problems. By utilizing advanced machine learning algorithms on a large database of ECG readings, the project aims to develop tools that can detect non-ST elevation myocardial events, which are often missed by traditional ECG methods. The goal is to create a real-time decision support system that can assist healthcare providers in making faster and more informed decisions at the bedside. This could lead to improved patient outcomes by ensuring timely treatment for those at risk of acute coronary events.

Why it matters

Potential benefit: If successful, this research could lead to faster and more accurate diagnoses for patients experiencing chest pain, potentially saving lives.

How similar studies have gone: Previous research has shown promise in using machine learning for ECG interpretation, indicating that this approach could be effective in clinical settings.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Al-Zaiti, Salah S — University of Pittsburgh at Pittsburgh
  • Study coordinator: Al-Zaiti, Salah S

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.