Improving early respiratory care for ALS patients at risk of respiratory failure
Official title: Early Respiratory Care in Amyotrophic Lateral Sclerosis Patients at High Risk for Respiratory Failure
Funded at University of Pennsylvania · NIH-11012778 · Data updated 2026-11-12
This study is looking to improve breathing care for people with ALS who might face serious breathing problems, by finding out who could benefit from early help and listening to their thoughts on treatments, so we can better support their needs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | January 1, 2021 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $196,458 |
| NIH project number | 5K23HL151879-05 |
| Project ID | NIH-11012778 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are ALS patients who are showing early signs of respiratory weakness and are at high risk for respiratory failure.
✕Less likely to help
Patients with advanced ALS who are already experiencing severe respiratory failure may not benefit from this research.
What this research studies
This research focuses on enhancing respiratory care for patients with amyotrophic lateral sclerosis (ALS) who are at high risk for respiratory failure. It aims to identify patients who may benefit from early interventions by using a clinical prediction tool that assesses the likelihood of respiratory complications. The study will explore patient perspectives on respiratory treatments, ensuring that their emotional and physical needs are considered. By understanding the different trajectories of respiratory function in ALS patients, the research seeks to tailor interventions more effectively.
Why it matters
Potential benefit: If successful, this research could lead to improved respiratory care strategies that significantly enhance the quality of life and survival rates for ALS patients.
How similar studies have gone: Previous research has shown promise in using clinical prediction tools for managing respiratory care in ALS, indicating that this approach could be effective.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Ackrivo, Jason — University of Pennsylvania
- Study coordinator: Ackrivo, Jason
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.