Improving early respiratory care for ALS patients at risk of respiratory failure

Early Respiratory Care in Amyotrophic Lateral Sclerosis Patients at High Risk for Respiratory Failure

NIH-funded research University of Pennsylvania · NIH-11012778

This study is looking to improve breathing care for people with ALS who might face serious breathing problems, by finding out who could benefit from early help and listening to their thoughts on treatments, so we can better support their needs.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11012778 on NIH RePORTER

What this research studies

This research focuses on enhancing respiratory care for patients with amyotrophic lateral sclerosis (ALS) who are at high risk for respiratory failure. It aims to identify patients who may benefit from early interventions by using a clinical prediction tool that assesses the likelihood of respiratory complications. The study will explore patient perspectives on respiratory treatments, ensuring that their emotional and physical needs are considered. By understanding the different trajectories of respiratory function in ALS patients, the research seeks to tailor interventions more effectively.

Who could benefit from this research

Good fit: Ideal candidates for this research are ALS patients who are showing early signs of respiratory weakness and are at high risk for respiratory failure.

Not a fit: Patients with advanced ALS who are already experiencing severe respiratory failure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved respiratory care strategies that significantly enhance the quality of life and survival rates for ALS patients.

How similar studies have performed: Previous research has shown promise in using clinical prediction tools for managing respiratory care in ALS, indicating that this approach could be effective.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Amyotrophic Lateral Sclerosis Motor Neuron Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.