Improving early detection of retinoblastoma in children using advanced imaging technology
Panretinal Circular Ranging OCT for Retinoblastoma
This study is testing a new handheld device that takes detailed pictures of the eye to help doctors find early signs of retinoblastoma, a type of eye cancer in kids, so they can catch it sooner and provide better care.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10789750 on NIH RePORTER |
What this research studies
This research focuses on enhancing the early diagnosis of retinoblastoma, a common childhood eye cancer, through innovative imaging techniques. By developing a new handheld optical coherence tomography (HH-OCT) device that provides high-resolution, three-dimensional images of the retina, the study aims to improve the detection of subclinical tumors that traditional methods may miss. The research will involve pilot imaging studies with sedated children to evaluate the effectiveness and feasibility of this new technology in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 11 years old, particularly those with a family history of retinoblastoma who are at higher risk for developing the disease.
Not a fit: Patients who are older than 11 years or those without a family history of retinoblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of retinoblastoma, potentially reducing visual impairment and improving survival rates in affected children.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for cancer detection, suggesting that this approach could be effective, although the specific application for retinoblastoma is relatively novel.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Jian, Yifan — Oregon Health & Science University
- Study coordinator: Jian, Yifan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.