Improving early detection of lung cancer using blood tests.

EFIRM Liquid Biopsy Research Laboratory: Early Lung Cancer Assessment

NIH-funded research University of California Los Angeles · NIH-10929472

This study is looking at a new way to help find lung cancer earlier by using blood tests to check for specific markers, which could help people with unclear lung nodules avoid unnecessary procedures.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10929472 on NIH RePORTER

What this research studies

This research focuses on enhancing the early detection of lung cancer through the use of liquid biopsies, which analyze tumor biomarkers found in blood samples. By developing personalized cancer-specific targets and refining technologies to detect these biomarkers, the project aims to differentiate between benign and potentially malignant pulmonary nodules identified through CT scans. Patients with indeterminate pulmonary nodules may benefit from non-invasive testing that could reduce the need for invasive procedures. The research is part of a larger effort to improve cancer assessment and outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have been identified with indeterminate pulmonary nodules through CT imaging.

Not a fit: Patients without any detected pulmonary nodules or those with confirmed lung cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and less invasive methods for diagnosing lung cancer at an early stage.

How similar studies have performed: Previous research has shown promise in using liquid biopsies for cancer detection, indicating that this approach may lead to significant advancements in early cancer assessment.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.