Improving early detection of lung cancer using advanced imaging techniques

Early Detection and Diagnosis of Lung Cancer with Endomicroscopy

['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10542357

This study is looking to make it easier and safer to find lung cancer early by using new imaging techniques during a simple procedure called bronchoscopy, especially for patients who are at high risk for the disease.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10542357 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the early diagnosis of lung cancer, which is crucial for improving patient survival rates. It aims to develop and utilize advanced optical imaging techniques to increase the accuracy of lung biopsies performed through bronchoscopy, a less invasive procedure. By improving the diagnostic yield of these low-risk procedures, the research seeks to minimize the need for more invasive surgical biopsies, which carry higher risks. Patients who are at high risk for lung cancer will be the primary focus of this investigation.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at high risk for lung cancer, particularly those who have been recommended for annual screening.

Not a fit: Patients who have already been diagnosed with lung cancer or those who do not meet the high-risk criteria for lung cancer screening may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and less invasive methods for diagnosing lung cancer, ultimately improving survival rates.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for improving diagnostic accuracy in various cancers, suggesting potential success for this novel approach.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancer Cause, Cancer Etiology, Cancers

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.