Improving early detection of liver cancer in patients with uncertain liver nodules
Precision Risk Stratification and Screening for HCC among Patients with Indeterminate Liver Nodules
This study is working on better ways to spot liver cancer early in people with uncertain liver nodules by using special blood tests and advanced imaging, so that patients can get the right level of monitoring based on their personal risk.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10931647 on NIH RePORTER |
What this research studies
This research focuses on enhancing the early detection of hepatocellular carcinoma (HCC) in patients who have indeterminate liver nodules. The team at the Translational Liver Cancer Research Center is developing a tailored approach that includes blood-based biomarkers and advanced imaging techniques to better stratify risk and optimize surveillance strategies. By analyzing patient data and incorporating cost-effective methods, the research aims to ensure that patients receive appropriate monitoring based on their individual risk levels. This could lead to earlier diagnosis and improved outcomes for those at risk of developing liver cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with indeterminate liver nodules who are at risk for developing hepatocellular carcinoma.
Not a fit: Patients without liver nodules or those with confirmed liver cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of liver cancer, improving survival rates and treatment outcomes for patients.
How similar studies have performed: Previous studies have shown success in using biomarkers and imaging for liver cancer detection, indicating a promising approach for this research.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Singal, Amit — Ut Southwestern Medical Center
- Study coordinator: Singal, Amit
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.