Improving early detection of liver cancer in patients with cirrhosis
Precision Screening for Hepatocellular Carcinoma in Patients with Cirrhosis
This study is working on finding better ways to catch liver cancer early in people with cirrhosis by creating personalized screening plans that take into account each person's unique risk factors, which could help doctors diagnose the cancer sooner and improve treatment outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10543119 on NIH RePORTER |
What this research studies
This research focuses on enhancing the early detection of hepatocellular carcinoma (HCC) in patients with cirrhosis by developing a precision screening strategy. It aims to create personalized screening approaches that consider individual risk factors and the performance of various screening tests. By analyzing data from 2000 patients, the study will evaluate new biomarkers and risk stratification models to improve the accuracy of early HCC detection. This could lead to more timely diagnoses and better outcomes for patients at risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cirrhosis who are at risk for developing hepatocellular carcinoma.
Not a fit: Patients without cirrhosis or those who do not have risk factors for hepatocellular carcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve early detection rates of liver cancer, leading to better survival outcomes for patients.
How similar studies have performed: Previous research has shown promise in using personalized approaches for cancer detection, indicating potential success for this novel strategy.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Singal, Amit — Ut Southwestern Medical Center
- Study coordinator: Singal, Amit
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.