Improving early detection of liver cancer
Clinical Validation Center for Hepatocellular Carcinoma
This study is looking for better ways to spot liver cancer early, especially for people with liver problems like cirrhosis, by testing new blood tests and imaging techniques to improve how we assess their risk.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10911035 on NIH RePORTER |
What this research studies
This research focuses on enhancing the early detection and risk assessment of hepatocellular carcinoma (HCC), a rapidly increasing cause of cancer death in the U.S. The project aims to validate new blood and imaging biomarkers through various phases of clinical studies, addressing the limitations of current screening methods that often miss early-stage cancers. By creating a contemporary resource of blood and imaging data, the research seeks to improve the accuracy of HCC risk stratification, particularly for patients with different underlying liver conditions. Patients with cirrhosis and other liver diseases will be central to this effort, as the research aims to provide more effective screening strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with cirrhosis or other liver diseases who are at risk for hepatocellular carcinoma.
Not a fit: Patients without liver disease or those who do not meet the criteria for HCC risk assessment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely detection of liver cancer, potentially improving survival rates for patients.
How similar studies have performed: Previous research has shown promise in using novel biomarkers for cancer detection, indicating potential for success in this approach.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Singal, Amit — Ut Southwestern Medical Center
- Study coordinator: Singal, Amit
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.