Improving early detection and treatment of sepsis in hospitalized patients

Sepsis Early Prediction and Subphenotype Illumination Study (SEPSIS)

NIH-funded research University of Wisconsin-Madison · NIH-11023032

This study is looking to improve how we spot and treat sepsis early by using health records and smart computer techniques, so we can help patients get the right care faster and ultimately save lives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison NIH-funded
Lab location1 site (Madison, United States)
Project IDNIH-11023032 on NIH RePORTER

What this research studies

This research focuses on enhancing the early prediction and treatment of sepsis, a severe condition caused by infections that can lead to organ failure. By analyzing extensive electronic health records and utilizing machine learning techniques, the study aims to identify patients at risk of developing sepsis more accurately and quickly. The research also seeks to understand the different biological responses to infections among patients, which can lead to more personalized treatment strategies. Ultimately, the goal is to reduce mortality and improve outcomes for those affected by sepsis.

Who could benefit from this research

Good fit: Ideal candidates for this research include hospitalized patients who are at risk of developing sepsis due to infections.

Not a fit: Patients who are not hospitalized or do not have infections that could lead to sepsis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly lower the rates of death and long-term complications associated with sepsis.

How similar studies have performed: Previous research has shown promise in using machine learning and biomarker analysis for improving sepsis detection and treatment, indicating that this approach has potential for success.

Where this research is happening

Madison, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.